Quality Care - everyone, everytime
 

2.6 Nitrates, calcium-channel blockers, and other antianginal drugs

NICE CG94 Management of unstable angina and NSTEMI Apr 10 
NICE CG126 Management of stable angina July 11
NICE CG127 Clinical management of primary hypertension in adults Aug 11

2.6.1 Nitrates

        GLYCERYL TRINITRATE   
      ISOSORBIDE MONONITRATE (and SR preparations)  

2.6.2 Calcium-channel blockers

1st       AMLODIPINE   
      NIFEDIPINE (ADALAT LA/ CORACTEN XL)  
2nd     LERCANIDIPINE (less ankle oedema experienced)  
3rd     LACIDIPINE  
      NIMODIPINE (Subarachnoid bleed)  
      VERAPAMIL (order by brand name only)  
      DILTIAZEM (order by brand name)  

2.6.3 Other antianginal drugs

      NICORANDIL    
        MHRA Drug Safety Update Nicorandil associated with a risk of gastrointestinal ulceration and perianal ulceration  June 08 
             
4th      RANOLAZINE (Ranexa) Limited role in stable angina where beta-blockers, calcium blockers contraindicated, not tolerated or ineffective
      IVABRADINE (Yellow) (Procoralan)    
        NICE TA267 Chronic heart failure - ivabradine Nov 12

2.6.4 Peripheral vasodilators and related drugs

      NAFTIDROFURYL     
        NICE TA223 Peripheral arterial disease - cilostazol, naftidrofyryl oxalate, pentoxifylline and inositol nicotinate  May 11 

 

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