Quality Care - everyone, everytime
 

2.8 Anticoagulants and protamine

 

NICE CG94  Unstable angina and NSTEMI Mar 10 
NICE CG92 Venous thromboembolism - reducing the risk Jan 10
IOW NHS Venous thromboembolism prophylaxisis policy  
IOW NHS Maternity Guidelines - Venous thromboembolism (VTE) in pregnancy  
IOW CCG Anticoagulation in NVAF  May 15

2.8.1 Parenteral anticoagulants

NICE TA230  Myocardial infarction (persistent ST - segment elevation) - Bivalirudin  Jul 11 
      ENOXAPARIN     
      FONDAPARINUX (Atrixa)  ED, MAU & CCU only  
      HEPARIN    
         Patient Safety Alert Risks associated with intravenous heparin flush solutions  April 08

2.8.2 Oral anticoagulants

1st line     WARFARIN  Warfarin remains the anticoagulant of choice.  If a patient is not responsive, unstable or has compliance complications then a NOAC may be prescribed   
2nd line     RIVAROXABAN  (Xarelto)    
        NICE TA335 Rivaroxaban for preventing adverse outcomes after acute management of acute coronary syndrome Mar 15
        NICE TA287 Pulmonary embolism and recurrent venous thromboemblism - rivaroxaban Jun 13
        NICE TA261 Rivaroxaban for the treatment of deep vein thrombosis and the prevention of recurrent deep vein thrombosis and pulmonary embolism Jul 12
        NICE TA256 Rivaroxaban for the prevention of stroke and systemic embolism in people with atrial fibrillation May 12
        NICE TA170 Venous Thromboembolism - Rivaroxaban Apr 09
2nd line     DABIGATRAN (Pradaxa)     
        NICE TA327 Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism Dec 14
        NICE TA249 Prevention of stroke and systemic embolism in atrial fibrillation Mar 12
        MHRA Drug Safety Update Dabigatran: Risk of serious haemorrhage - need for renal function testing Dec 11
        NICE TA157 Venous Thromboembolism Sept 08 
      IDARUCIZUMAB (Praxbind)  For emergency reversal of dabigatran  
2nd line (1st line NOAC in poor renal function)     APIXABAN (Eliquis)       
        NICE TA341  Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism  Jun 15
        NICE TA275  Apixaban for preventing stroke and systemic embolism in people with nonvalvular atrial fibrillation  Feb 13
        NICE TA245  Venous thromboembolism - apixaban (hip and knee surgery)  Jan 12
             
2nd line (2nd line NOAC in poor renal function)     EDOXABAN (Lixiana)     
         NICE TA355 Edoxaban for preventing stroke and systemic embolism in people with non valvular AF Sept 15
         NICE TA354 Edoxaban for treating and preventing DVT & PE Aug 15

2.8.3 Protamine sulphate

        PROTAMINE   

 

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