8.1 Cytotoxic Drugs
NICE Guidance Cancer
Chemotherapy drugs are frequently given in combination.
Disease specific protocols are approved at local and network level.
Only approved protocols should be used. All chemotherapy treatment decisions should be made by a consultant grade oncologist or haematologist, with input from the relevant multidisciplinary team.
Chemotherapy drugs, including oral therapies must be prescribed, dispensed and administered only by suitable trained staff.
Paediatric cancer therapies are initiated and prescribed from tertiary cancer centres. The exception is maintenance treatment for some cancers, which is prescribed by designated paediatricians only.
| Chemotherapy Mouth Care | |
| GELCLAIR | |
| EPISIL Mouthwash | |
| CAPHOSOL Mouthwash |
|
Treatment for cytotoxity-induced side effects |
|
| Urothelial toxicity | |
| MESNA Tabs | |
| Chemotherapy-induced mucositis and myelosuppression | |
| FOLINIC ACID Inj | |
| 8.1.1 Alkylating drugs | |
| BENDAMUSTINE | |
| BUSULFAN | |
| CHLORAMBUCIL | |
| CYCLOPHOSPHAMIDE Inj & Tabs | |
| LOMUSTINE | |
| MELPHALAN | |
| 8.1.2 Anthracyclines and other cytotoxic antibiotics | |
| DOXORUBICIN | |
| EPIRUBICIN | |
| MITOMYCIN - C | |
| MITOXANTRONE | |
| 8.1.3 Antimetabolites | |
| AZACITADINE | |
| CAPECITABINE | |
| CYTARABINE | |
| FLUDARABINE | |
| FLUOROURACIL | |
| GEMCITABINE | |
| MERCAPTOPURINE (Amber) | |
| METHOTREXATE | |
| PEMETREXED | |
| RALTITREXED | |
| 8.1.4 Vinca alkaloids and etoposide | |
| ETOPOSIDE | |
| VINDESINE | |
| VINORELBINE (Inc oral) | |
| 8.1.5 Other antineoplastic drugs | |
| AFLIBERCEPT | |
 |
AXITINIB (Inlyta) |
| BEVACIZUMAB | |
| BORTEZOMIB | |
| CABAZITAXEL NICE TA391 | |
| CARBOPLATIN | |
| CERITINIB NICE TA395 | |
| CETUXIMAB | |
| CISPLATIN | |
| DOCETAXEL | |
| ERLOTINIB | |
| GEMCITABINE | |
| HYDROXYCARBAMIDE (Yellow) | |
| IMATINIB | |
| IRINOTECAN | |
| OXALIPLATIN | |
| PACLITAXEL | |
| TOPOTECAN | |
| TRASTUZUMAB | |
| VINCRISTINE | |
| VINORELBINE | |
