Quality Care - everyone, everytime
 

8.1 Cytotoxic Drugs

NICE Guidance Cancer

Chemotherapy drugs are frequently given in combination.

Disease specific protocols are approved at local and network level.

Only approved protocols should be used. All chemotherapy treatment decisions should be made by a consultant grade oncologist or haematologist, with input from the relevant multidisciplinary team.

Chemotherapy drugs, including oral therapies must be prescribed, dispensed and administered only by suitable trained staff.

Paediatric cancer therapies are initiated and prescribed from tertiary cancer centres. The exception is maintenance treatment for some cancers, which is prescribed by designated paediatricians only.

Chemotherapy Mouth Care   
 GELCLAIR  
 EPISIL Mouthwash  
 CAPHOSOL Mouthwash  

Treatment for cytotoxity-induced side effects

   
Urothelial toxicity
  MESNA Tabs
Chemotherapy-induced mucositis and myelosuppression
  FOLINIC ACID Inj
   
8.1.1 Alkylating drugs
  BENDAMUSTINE
  BUSULFAN
  CHLORAMBUCIL
  CYCLOPHOSPHAMIDE Inj & Tabs
  LOMUSTINE
  MELPHALAN
   
8.1.2 Anthracyclines and other cytotoxic antibiotics
  DOXORUBICIN
  EPIRUBICIN
  MITOMYCIN - C
  MITOXANTRONE
   
8.1.3 Antimetabolites
  AZACITADINE
  CAPECITABINE
  CYTARABINE
  FLUDARABINE
  FLUOROURACIL
  GEMCITABINE
  MERCAPTOPURINE (Amber)
  METHOTREXATE
  PEMETREXED
  RALTITREXED
   
8.1.4 Vinca alkaloids and etoposide
  ETOPOSIDE
  VINDESINE
  VINORELBINE (Inc oral)
   
8.1.5 Other antineoplastic drugs
  AFLIBERCEPT
AXITINIB (Inlyta)
  BEVACIZUMAB
  BORTEZOMIB
  CABAZITAXEL NICE TA391
  CARBOPLATIN
  CERITINIB NICE TA395
  CETUXIMAB
  CISPLATIN
  DOCETAXEL
  ERLOTINIB
  GEMCITABINE
  HYDROXYCARBAMIDE (Yellow)
  IMATINIB
  IRINOTECAN
  OXALIPLATIN
  PACLITAXEL
  TOPOTECAN
  TRASTUZUMAB
  VINCRISTINE
  VINORELBINE

 

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